FACTS ABOUT NAD+ AND ITS ROLE IN MITOCHONDRIAL FUNCTION REVEALED

Upcoming, we dealt with cells with different concentrations of NAD+. When additional for 24 h at 80 µM in HeLa and four hundred µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Prolonged Details Fig. 1k,l). Also, sixteen µM of NAD+ was sufficient to lessen fork velocity by ~40% in HeLa cells without the need of affec